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Abstract #3721

Distinguishing sonic hedgehog from Group 4 medulloblastoma using amide proton transfer–weighted MR Imaging

AnDong Ma1, YaoMing Qu1, MingJun Lu1, Xia Zou1, XinZi Liu1, Chen Zhao2, and ZhiBo Wen1
1Radiology, ZhuJiang Hospital of Southern Medical University, GuangZhou, China, 2Philips Healthcare, GuangZhou, China


Preoperative prediction of molecular subgroup based on magnetic resonance imaging (MRI) remains a challenge. The objective of this study was to assess amide proton transfer-weighted (APTw) method in medulloblastoma (MB). Preliminary results showed that the mean value of APT value in sonic hedgehog (SHH) -activated MB tended to be higher than that of Group 4 MB.

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