Abstract #3723

The value of IVIM and mDIXON-Quant MR imaging in the identification of pediatric IgAN and HSPN

Yupeng Zhu¹, Yun Peng¹, Xiaorong Liu², Jianxiu Lian³, Zhiwei Shen³, and Geli Hu³

¹Radiology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China, ²Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China, ³Philips Healthcare, Beijing, China

Synopsis

It is difficult to identify IgA nephropathy (IgAN) and Henoch Schonlein purpura nephritis (HSPN) due to their similar clinical features. Functional magnetic resonance imaging (fMRI) can simultaneously obtain tissue structure and function imaging, and evaluate the functional state of kidney. In this study, intravoxel incoherent motion (IVIM) and mDIXON-Quant were performed in pediatric patients with nephropathy, and it was found that IgAN and HSPN were remarkably different in renal function. The values of medulla’s D and cortex’s R2* obtained by IVIM and mDIXON-Quant had the ability in differential diagnosis of IgAN and HSPN.

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