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Abstract #3724

The value of synthetic MRI in detecting the brain change and hearing impairment of children with sensorineural hearing loss

Penghua Zhang1, Xiaoan Zhang1, Xin Zhao1, Lin Lu1, Jinxia Guo2, Qingna Xing1, Meiying Cheng1, and Lingsong Meng1
1The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2MR Research,GE Healthcare,Beijing,China, Beijing, China


Study explored the brain development of children with sensorineural hearing loss (SNHL),which may cause children's language discrimination ability and voice localization ability worse.The auditory pathway was regarded impaired and the related brain structure may change in SNHL,especially in early development stage for children age less than 3 months.Studies with Diffusion tensor imaging,diffusion kurtosis imaging and fMRImainly investigate the patient age over 2 years old,when its a timechildren's brain is myelinated[1] .

Synthetic MRI was used in this study to quantitatively evaluate the differences among normal and SNHL with varying degree of hearing loss. The quantitative value of T1 in inferior colliculus,lateral lemniscus and middle cerebellar peduncle were found help early diagnosis of hearing loss of SNHL infants.

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