SvO2 and CMRO2 in patients with sickle cell anemia (SCA) were evaluated by MR susceptibility-based oximetry and compared with that derived from T2-based methods. The results show that (1) SvO2 trends lower and OEF tends to be higher in T2-based methods, (2) there is high correlation of CMRO2 between SBO and HbS model, (3) CMRO2 derived from SBO indicates tCBF was elevated to maintain oxygen delivery and oxygen metabolism in the brain given that CMRO2 is comparable with the healthy subjects reported previously. The preliminary results demonstrate the feasibility of OEF and CMRO2 estimation via SBO in subjects with SCA.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords