Abstract #3751

Blood Oxygen Level-Dependent Imaging of Lower Limbs: Perfusion and Clinical Assessment of Peripheral Artery Disease

Xiaoxi Yu¹, Zhaoxi Liu², Jianxun Qu³, Fengdan Wang², Zhichao Lai¹, Jiangyu Ma¹, Xiaoyuan Fan², Luming Ye⁴, Jiang Shao¹, Yan Zhang², Feng Feng², Bao Liu¹, and Zhengyu Jin²

¹Vascular Surgery, Peking Union Medical College Hospital, Beijing, China, ²Radiology, Peking Union Medical College Hospital, Beijing, China, ³Siemens Healthineers Ltd., Beijing, China, ⁴Advanced Therapies Collaboration, Siemens Healthineers Ltd., Beijing, China

Synopsis

This study used blood oxygen level-dependent (BOLD) MRI to assess the hemodynamics of the lower limbs for patients with peripheral artery disease. We obtained dynamic change of BOLD T2* with high temporal and spatial resolution in reactive hyperemia experiment and found good correlation between BOLD parameters and clinical walking performance, which verified the significance of perfusion measurement for clinical assessment.

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