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Abstract #3751

Blood Oxygen Level-Dependent Imaging of Lower Limbs: Perfusion and Clinical Assessment of Peripheral Artery Disease

Xiaoxi Yu1, Zhaoxi Liu2, Jianxun Qu3, Fengdan Wang2, Zhichao Lai1, Jiangyu Ma1, Xiaoyuan Fan2, Luming Ye4, Jiang Shao1, Yan Zhang2, Feng Feng2, Bao Liu1, and Zhengyu Jin2
1Vascular Surgery, Peking Union Medical College Hospital, Beijing, China, 2Radiology, Peking Union Medical College Hospital, Beijing, China, 3Siemens Healthineers Ltd., Beijing, China, 4Advanced Therapies Collaboration, Siemens Healthineers Ltd., Beijing, China


This study used blood oxygen level-dependent (BOLD) MRI to assess the hemodynamics of the lower limbs for patients with peripheral artery disease. We obtained dynamic change of BOLD T2* with high temporal and spatial resolution in reactive hyperemia experiment and found good correlation between BOLD parameters and clinical walking performance, which verified the significance of perfusion measurement for clinical assessment.

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