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Abstract #3766

Dynamic Contrast-Enhanced T1 Mapping: Repeatability, Reproducibility, and Differentiating Clear Cell Renal Cell Carcinoma from Non-ccRCC

Shuai Wang1, Binghui Zhao1, Jilei Zhang2, and Weibo Chen2
1Radiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China, 2Philips Healthcare, Shanghai, China


T1 mapping is a quantitative MR technique that can be used to measure the longitudinal relaxation time of tissues. Previous studies demonstrated that it is potentially able to differentiate benign and malignant tumors and identify histopathological grade. In this study, the dynamic contrast enhanced (DCE) T1 mapping exhibited the robust reproducibility and repeatability and thus may have potential be used for quantitative renal tumor evaluation in cross-sectional and longitudinal studies. Furthermore, we found that clear cell renal cell carcinoma (ccRCC) had higher native and enhanced T1values than non-ccRCC. Thus, DCE T1 mapping is promising in differentiating ccRCC from non-ccRCC.

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