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Abstract #3791

Differentiating metastatic from nonmetastatic lymph nodes in cervical cancer patients by IVIM-DWI and DKI

Suixing Zhong1, Ya Zhang1, Yingying Ding1, Xiaoyong Zhang2, Jing Tan1, Conghui Ai1, Yan Jin1, Hongbo Wang1, Huimei Zhang1, Miaomiao Li1, Rong Zhu1, and Shangwei Gu1
1Department of Radiology, Yunnan Cancer Hospital, Third Affiliated Hospital of Kunming Medical University, Kunming, China, 2Clinical Science, Philips Healthcare, Chengdu, China

Synopsis

This study aimed to investigate the diagnostic value of intravoxel incoherent motion (IVIM) diffusion-weighted imaging and diffusion kurtosis imaging (DKI) in distinguishing metastatic from nonmetastatic lymph nodes (LNs) in cervical cancer patients. The clinical and imaging data of 102 patients with cervical cancer were collected prospectively, including 38 patients with LN metastasis and 64 patients without LN metastasis. The morphological parameters, diffusion parameters and tumor markers of primary tumors and LNs were measured and compared between the two groups. The results showed that the diagnostic efficiency of diffusion parameters were not as good as morphological parameters.

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Keywords