Resting-state fMRI was used to investigate the aging effect on caudate function in mild cognitively impaired participants, with the focus of sex-dependent effect. Graph theory analysis was conducted to derive caudate nodal strength, which was then input to linear mixed effect model to evaluate its association with age. A striking aging effect was observed only in women with MCI but not in men with MCI, which was closely related to cognitive decline in woman participants. This finding suggests that caudate may be critical for alleviating cognitive decline in women with MCI.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords