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Abstract #3814

Histogram analysis of T1 Mapping and Diffusion-Weighted Imaging in the Prediction of Grades, Subtypes and Proliferation Status of Meningiomas

Tiexin Cao1, Lin Lin1, Yunjing Xue1, Pu-Yeh Wu2, Rufei Zhang1, and Lingmin Zheng1
1Fujian Medical University Union Hospital, Fuzhou, China, 2GE Healthcare, Beijing, China


In daily clinical practice, preoperative grading of meningioma is particularly important for selecting the best treatment strategy. Our hypothesis is that a combination of T1 mapping and diffusion weighted imaging (DWI) based on histogram analysis would be useful for differentiating between low-grade and high-grade meningiomas. Our study, for the first time, provides evidence that T1 mapping may be an imaging biomarker for differentiating grades and predicting the proliferation potential of meningiomas. The combination of T1 mapping and DWI showed the highest diagnostic performances in grading meningiomas.

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