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Abstract #3813

Pancreatic extracellular volume fraction using T1 mapping in patients with liver cirrhosis

Qinhe Zhang1, Nan Wan1, Xue Ren1, Peng Sun2, Xu Dai3, Liangjie Lin4, Zhigang Wu5, Jiazheng Wang4, and Ailian Liu1
1The first affiliated hospital of Dalian Medical University, Dalian, China, 2Philips health, Wu han, China, 3Philips health, Shenyang, China, 4Philips health, Beijing, China, 5Philips health, Shen zhen, China


Extracellular volume (ECV) fraction might represent a useful parameter for the noninvasive quantification of pancreatic fibrosis, and the proton density fat fraction (FF) of pancreas can be obtained by mDxion Quant. Here, we hypothesized that pancreatic ECV and FF, for evaluation of pancreatic fibrosis and fat content, can be used to assess patients with liver cirrhosis. Results indicated that pancreatic ECV at 60 mins after contrast agent administration showed a statistical difference between liver cirrhosis patients and controls. A significant correlation was observed between pancreatic FF and ECV at 5 mins after administration.

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