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Abstract #3862

Quantitatively Evaluating the Effect of Fat on ADC Measurement in EP-DWI and PROPELLER-DWI Using Fat-Water Phantom

Jo-Hua Peng1, Chun-Jung Juan1,2,3, Yi-Jui Liu4, Ruey-Hwang Chou5, Hing-Chiu Chang6, Chang-Hsien Liou2,7, Szu-Hsien Chou1,2, Yen-Ting Wu1,2, Bai-Wen Wu2, and Hsu-Hsia Peng1
1Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, 2Department of Medical Imaging, China Medical University Hsinchu Hospital, Hsinchu, Taiwan, 3Department of Radiology, School of Medicine, China Medical University, Taichung, Taiwan, 4Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, 5Institute of Cancer Biology, China Medical University, Taichung, Taiwan, 6Department of Biomedical Engineering, Chinese University of Hong Kong, Sha Tin, Hong Kong, 7Institute of Nuclear Engineering and Science, National Tsing Hua University, Hsinchu, Taiwan


ADC estimations are still known to be influenced by the content of fat. Fat suppression is normally applied in order to avoid the ADC measurement with fat contamination. The aim of this study was to evaluate the fat effect on ADC measurement by EP-DWI and PROP-DWI combined with different fat suppression techniques using a fat-water phantom with different fat fractions. Our results suggest that the ADC measurement is affected by the fat fraction and the MR sequences but not the fat suppression methods in EP-DWI.

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