Resting-state functional connectivity based on simultaneous BOLD oscillations has been described both in preterm infants and fullterm newborns. During this period of rapid cerebral cortex development, different brain activity patterns (networks) have been previously described. Regional changes in spontaneous BOLD signal variability on the other hand reflect local intravoxel BOLD changes related to neural excitability/flexibility. In the present study, we aimed to explore the longitudinal evolution of the BOLD variability between birth and term-equivalent-age (TEA), a period of rapid brain development, in preterm-born infants. Our findings suggest increased variability at TEA as compared to birth in important primary cortices.
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