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Abstract #3895

Phase-Sweep Method and Fitting Analysis in Slow CSF Shunt Flow Measurement with PS-FENSI

Mingxiao Zhang1, Aaron Anderson2,3, Paul Arnold3, Jason Huston3, William C. Olivero2, and Bradley P. Sutton1,2
1Department of Bioengineering, University of Illinois, Urbana, IL, United States, 2Beckman Institute, Urbana, IL, United States, 3Carle Foundation Hospital, Urbana, IL, United States


Pediatric patients with hydrocephalus rely on ventriculo-peritoneal shunts to drain cerebrospinal fluid (CSF) from the brain. Quick, safe detection of shunt failure is crucial to preventing neurologic injury. Previously, a non-invasive MRI-based monitoring technique, Shunt Flow Enhancement of Signal Intensity (Shunt-FENSI), was proposed for accurate and quantitative CSF flow measurement in the slow flowing shunt. We are introducing a more advanced version, Phase-Sweep FENSI (PS-FENSI) to deal with magnetic field inhomogeneity which can cause changes to the tag effectiveness. This new method is accompanied by new fitting methods to more reliably measure FENSI signals.

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