Abstract #3904

Spatial alignment of structural images on common and RESOLVE diffusion images in the optic nerve

Markus Janko^1,2, Patrick Rose^1,2, Vanessa Ines Schoeffling¹, Oliver Korczynski¹, Katharina Ponto³, Esther Hoffmann³, Marc Brockmann¹, Wolfgang Kleinekofort², and Andrea Kronfeld¹

¹Neuroradiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany, ²Applied Physics & Medical Engineering, Hochschule RheinMain, Rüsselsheim, Germany, ³Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany

Synopsis

A successful use of anatomical templates in the evaluation of functional neuroimaging-studies is only possible, if anatomical and functional intra-individual data can be registered with sufficient accuracy. We wanted to investigate the possibility to register structural on common and RESOLVE diffusion-images of the optic nerve. Three volunteers were examined and the structural images were registered to the two diffusion-datasets. Two observers defined seeds for tractography of the optic nerve on the structural and on the diffusion images. Tractography worked with seeds defined on the structural images registered to RESOLVE. Therefore RESOLVE is suitable for the use in template-based studies.

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