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Abstract #3940

Development of in vivo human brain DTI-MRE: Preliminary results

Shujun Lin1, Brad Sutton2, Richard Magin1, Aaron Anderson2, and Dieter Klatt1
1Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States, 2Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States


Simultaneous acquisition of diffusion tensor imaging (DTI) and magnetic resonance elastography (MRE) has been proven feasible in a pre-clinical study and in preliminary studies of in vivo human brain. However, the experimental parameters have to be optimized in order to prevent mutual interferences of DTI and MRE acquisitions. We identified in simulations two experimental parameter sets for in vivo human brain DTI-MRE that we classify as good and moderate and present a pilot study using these parameter sets. The experimental results indicate that both experimental parameter sets show good performance using motion-encoding gradients without flow compensation.

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