Abstract #3995

Multi-site, longitudinal assessment of quantitative breast MRI variability using the CaliberMRI phantom

Jessica Gibbs¹, Nu Le¹, Todor Karaulanov², Lisa Wilmes¹, David Newitt¹, Kathryn Keenan³, Bonnie Joe¹, and Nola Hylton¹

¹University of California, San Francisco, San Francisco, CA, United States, ²CaliberMRI, Boulder, CO, United States, ³National Institute of Standards and Technology, Boulder, CO, United States

Synopsis

Quantitative breast MRI data was acquired at seven clinical sites using the CaliberMRI phantom. T1 and DWI data were acquired, and the qCal software was used for analysis. Protocol adherence was assessed, quantitative measures were automatically derived, and variability between measurements was evaluated. Going forward, the phantom will be used for calibration as part of a program to assess quantitative accuracy in a large multi-site clinical trial. The phantom program will be expanded to other sites in the trial, with standardized reporting used to understand variability across sites.

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