We validated prostate tissue composition measured using HM-MRI by comparing with reference standard results from pathologists’ interpretation of clinical histopathology slides following whole mount prostatectomy. We are 95% confident that 90% of absolute paired differences (TDI0.9) between HM-MRI and consensus results of pathologists were within 20.6% and 24.2% in measuring epithelium and lumen fractional volumes, respectively. These were less than our criterion of 30% and inter-pathologists’ agreement (22.3% for epithelium and 24.2% for lumen). Therefore, we accept the agreement performance of HM-MRI in measuring tissue composition measurement and consensus of pathologists is on par with the inter-raters (pathologists) agreement.
This abstract and the presentation materials are available to members only; a login is required.