Lean body mass (LBM) is an important measure of metabolic ability. Decreased LBM during infancy may be associated with impaired growth and increased risk for future metabolic disease. This study measured skeletal muscle area as a surrogate for LBM in infants using free-breathing MRI. Psoas and paraspinal muscle areas were measured in 14 infants at the L4-L5 intervertebral disc level. Cross-sectional area of the thigh muscles was measured at the right midthigh in 8 infants. Infants with higher birth weights and those born large for gestational age had larger muscle areas than infants born lighter and/or small for gestational age.
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