Assessment of SAR variability across early gestational age subjects at 3T fetal MRI
Esra Abaci Turk1,2, Filiz Yetisir1, Cindy Zhou1, Jeffrey N. Stout1, Judy A. Estroff3,4, Carol Barnewolt3,4, Elfar Adalsteinsson5,6,7, P. Ellen Grant1,2, and Lawrence L. Wald2,6,8
1Fetal‐Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Boston, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3Department of Radiology, Boston Children’s Hospital, Boston, MA, United States, 4Maternal Fetal Care Center, Boston Children’s Hospital, Boston, MA, United States, 5Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 6Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, 7Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 8Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States
Despite the clinical and research potential of fetal MRI, there is no consensus on MRI safety in the 1st and early 2nd trimesters. Prior simulation studies at early gestational ages (GA) used only a single or unrealistic pregnant body models. To address this gap, we built 2 realistic uterine models for the early 2nd trimester and placed them into 3 existing pregnant body models at a later GA to investigate differences in RF exposure. Lower pSAR10g in both the fetus and amniotic fluid was observed in the early 2nd trimester models compared to later GA models.
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