Abstract #4021

Assessment of SAR variability across early gestational age subjects at 3T fetal MRI

Esra Abaci Turk^1,2, Filiz Yetisir¹, Cindy Zhou¹, Jeffrey N. Stout¹, Judy A. Estroff^3,4, Carol Barnewolt^3,4, Elfar Adalsteinsson^5,6,7, P. Ellen Grant^1,2, and Lawrence L. Wald^2,6,8

¹Fetal‐Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Boston, MA, United States, ²Harvard Medical School, Boston, MA, United States, ³Department of Radiology, Boston Children’s Hospital, Boston, MA, United States, ⁴Maternal Fetal Care Center, Boston Children’s Hospital, Boston, MA, United States, ⁵Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁶Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁷Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁸Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States

Synopsis

Despite the clinical and research potential of fetal MRI, there is no consensus on MRI safety in the 1st and early 2nd trimesters. Prior simulation studies at early gestational ages (GA) used only a single or unrealistic pregnant body models. To address this gap, we built 2 realistic uterine models for the early 2nd trimester and placed them into 3 existing pregnant body models at a later GA to investigate differences in RF exposure. Lower pSAR10g in both the fetus and amniotic fluid was observed in the early 2nd trimester models compared to later GA models.

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