Abstract #4031
Mapping Brain Development in Infants and Young Children Using MPnRAGE T1 Relaxometry
Douglas Dean1,2,3, Leela Shah3, Marissa DiPiero3,4, Colleen Pletcher3, Lauren Heinrich3, Elizabeth Planalp3, Andrew Alexander2,3,5, and Steven Kecskemeti3
1Pediatrics, University of Wisconsin–Madison, Madison, WI, United States, 2Medical Physics, University of Wisconsin–Madison, Madison, WI, United States, 3Waisman Center, University of Wisconsin–Madison, Madison, WI, United States, 4Neuroscience Training Program, University of Wisconsin–Madison, Madison, WI, United States, 5Psychiatry, University of Wisconsin–Madison, Madison, WI, United States
Synopsis
Quantitative magnetic resonance imaging during the first years of life can provide novel insights into brain maturation, yet acquisition of these data are limited by challenges in imaging pediatric populations. Here, we assessed the self-navigated, motion robust MPnRAGE technique to acquire high-resolution T1-weighted structural brain images and quantitative T1 relaxometry maps in infants and young children. Our results demonstrate the ability to utilize MPnRAGE as a robust quantitative technique to assess early brain development.
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