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Abstract #4052

Optimizing k-space averaging patterns for advanced denoising-reconstruction methods

Jiayang Wang1 and Justin P. Haldar1
1Signal and Image Processing Institute, Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States

Synopsis

This work investigates the potential value of combining non-uniform k-space averaging with advanced nonlinear image denoising-reconstruction methods in the context of low-SNR MRI. A new data-driven strategy for optimizing the k-space averaging pattern is proposed, and is then applied to total variation and U-net reconstruction methods. It is observed that non-uniform k-space averaging (with substantially more averaging at the center of k-space) is preferred for both reconstruction approaches, although the distribution of averages varies substantially depending on the noise level and the reconstruction method. We expect that these results will be informative for a wide range of low-SNR MRI applications.

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