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Abstract #4063

Improved Phase-cycling Preparations in Quantitative T1rho Mapping

Gregory Peng1, Can Wu2, and Qi Peng1
1Department of Radiology, Albert Einstein College of Medicine, Bronx, NY, United States, 2Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States


Phase-cycling (PC) has been proposed as an effective method to minimize the impact of B0 and B1 field inhomogeneities in quantitative T1rho mapping, which needs both positive and negative longitudinal magnetization T1rho preparations. We propose here a simple magnetization inversion with an adiabatic inversion RF pulse before an established T1ρ preparation module to achieve an opposite PC. This approach has been shown to be much less sensitive to B0/B1 field imperfections compared with a traditional approach of reversing the phase of the last 90° RF pulse.

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