We explore the feasibility of noninvasive temperature measurement around deep brain stimulation (DBS) leads using magnetic resonance fingerprinting (MRF) by leveraging 1) the dependency of T1 on temperature; 2) MRF’s efficient T1 and B0 mapping. We conducted a T1 and temperature calibration experiment and a lead calorimetry experiment on bovine muscle. The effects of B0 inhomogeneity and temperature profiles of different regions of interest (ROI) were investigated. The calibration showed a strong correlation between temperature and T1 (R2>0.98). We observed a maximum change of 10.2 oC near leads (~1mm away) during calorimetry experiments, validated by fluoroptic probes.
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