Due to their low cytoplasmic capacity and phagocytic activity, T cells have consistently been challenging to label for MR tracking applications. We developed a one-stop shop approach where the T cell sorting agent also labels the cells which can subsequently be imaged using non-invasive MRI. We demonstrate positive intracellular localization of the beads in Treg cells by means of histopathology analyses and MRI signal effects in phantoms containing different amounts of labeled cells.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords