The repeatability of fast 3D T1 mapping using MP-GRASP (Magnetization-Prepared Golden-angle RAdial Sparse Parallel) MRI and its robustness to variation of imaging parameters including flip angle in phantom and brain were demonstrated. The experiments showed that MP-GRASP has a good robustness to B1 inhomogeneity, with intra-slice repeatability below 1% in the single tube phantom experiment. The longitudinal experiments also yielded good repeatability both in phantom (<2.5%) and in the brain (<2%) under various imaging conditions. The T1 values estimated are accurate relative to inversion recovery spin echo (IR-SE) gold standard (R2=0.997, Lin’s CCC=0.996).
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