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Abstract #4099

Repeatability and Robustness of MP-GRASP T1 Mapping

Zhitao Li1, Yang Yang2, and Li Feng2
1Department of Radiology, Stanford University, Palo Alto, CA, United States, 2Biomedical Engineering and Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States


The repeatability of fast 3D T1 mapping using MP-GRASP (Magnetization-Prepared Golden-angle RAdial Sparse Parallel) MRI and its robustness to variation of imaging parameters including flip angle in phantom and brain were demonstrated. The experiments showed that MP-GRASP has a good robustness to B1 inhomogeneity, with intra-slice repeatability below 1% in the single tube phantom experiment. The longitudinal experiments also yielded good repeatability both in phantom (<2.5%) and in the brain (<2%) under various imaging conditions. The T1 values estimated are accurate relative to inversion recovery spin echo (IR-SE) gold standard (R2=0.997, Lin’s CCC=0.996).

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