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Abstract #4128

Co-registration of cardiac PET and late gadolinium enhancement MRI for integrated PET/MR

zheng zhang1,2, Xing Chen3, Zhiwen You3, Jianmin Yuan2, Lingzhi hu4, Jun Zhao3, and Chenxi Hu1
1Shanghai Jiao Tong University, Shanghai, China, 2United Imaging Healthcare Co. Ltd., Shanghai, China, 3Shanghai East Hospital, Shanghai, China, 4United Imaging Healthcare Co. Ltd., Houston, TX, United States


A two-stage cardiac PET/late gadolinium enhancement (LGE) co-registration method proposed here significantly improved the co-registration between PET and LGE in integrated PET/MR imaging. The two-stage method led to increased registration score (4.93±0.89) versus no-registration (3.49±0.84, p<0.001) and a single-stage method (4.23±0.81, p<0.001), an increased SUV value in the normal myocardium (3.87±2.56) compared with the no-registration (3.14±1.92, p<0.001) and the single-stage method (3.32±2.16, p<0.001). The technique may improve diagnostic accuracy of non-ischemic cardiomyopathies via better image co-registration.

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