This study mainly explored the feasibility of high-resolution vascular wall magnetic resonance imaging（HR-VW-MRI）in evaluating the treatment effect for patient with middle cerebral artery (MCA) recanalization. We included 21 patients with MCA stenosis diagnosed by DSA. All patients were treated with SeQuent Please drug-coated balloon recanalization and performed with HR-VW-MRI examination. Decreased responsible plaque area, length, enhancement index and lumen stenosis degree were found in MCA postoperatively. Additionally, the lumen stenosis degree evaluated by HR-VW-MRI was highly correlated with DSA. Therefore, HR-VW-MRI could be used as a valuable method to diagnose the effect of vascular recanalization.