3D free-breathing simultaneous whole heart T1 and T2 mapping based on SAturation Recovery and Variable flip Angle (SAVA)
Dongyue Si1, Rui Guo2, Bowei Liu1, Daniel A. Herzka3, and Haiyan Ding1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China, 2Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, 3National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States
Myocardial T1 and T2 mapping enable quantitative detection of various cardiac diseases. Here we propose a fast 3D free-breathing simultaneous T1 and T2 mapping sequence, which acquires four volumes for joint estimation of T1 and T2. A very small flip angle is used for efficient sampling of the equilibrium longitudinal magnetization. Whole-heart T1 and T2 maps were acquired with high resolution of 1.5×1.5×4mm3 within 5 min in normal human subjects with image quality comparable to conventional 2D methods.
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