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Abstract #4157

The feasibility of radiomic analysis based on T1 mapping to distinguish between hypertensive heart disease and hypertrophic cardiomyopathy

Shengliang Liu1, Jianxiu Lian2, Haixia Li2, Guokun Wang1, Yunling Li1, Yanming Zhao1, Bing Xu1, and Bo Yu1
1Department of Cardiology, the Second Affiliated Hospital of Harbin Medical University, Harbin, China, 2Philips Healthcare, Beijing, China


Hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD) share similar features, such as thickened left ventricular (LV) wall and reduced compliance, which make it difficult to distinguish HCM from HHD clinically. In this retrospective study, patients with HCM and HHD were enrolled to evaluate the feasibility of radiomic analysis to differentiate between these two diseases. For all calculated texture analysis (TA) features, AUCs of nine parameters had the values above 0.65, Logarithm_glszm_ZoneEntropy reached the best performance than other parameters (AUC: 0.790, sensitivity: 71.4 %, specificity: 81.8 %, P < 0.01).

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