Abstract #4164

Left ventricular diastolic dysfunction in uncomplicated obesity: evaluated by CMR tissue tracking and volume-time curve

Jing Liu¹, Jing Li², Huaxia Pu¹, Wenzhang He¹, Xue Li¹, Xiaoyue Zhou³, Nanwei Tong², and Liqing Peng¹

¹Radiology, West China Hospital, Sichuan University, Chengdu, China, ²Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China, ³MR Collaboration, Siemens Healthineers Ltd., Shanghai, China

Synopsis

This study evaluated left ventricular (LV) diastolic functional changes and left atrial (LA) functional indices using cardiac magnetic resonance (CMR) tissue tracking and volume-time curve in obese adults with no clinical signs or comorbidities. The association of LV diastolic function with fat distributions was also assessed. The results showed that CMR detected subclinical LV diastolic dysfunction, impaired LA reservoir and conduit function with preserved LV ejection fractions in adults with obesity. LV diastolic function was associated with LA reservoir and conduit function. Visceral fat was deleterious for LV diastolic function, while peripheral obesity might have had a protective effect.

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