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Abstract #4163

Regional fat distributions are associated with subclinical right ventricular dysfunction in adults with uncomplicated obesity

Jing Liu1, Jing Li2, Huaxia Pu2, Wenzhang He1, Xue Li1, Xiaoyue Zhou3, Nanwei Tong2, and Liqing Peng1
1Radiology, West China Hospital, Sichuan University, Chengdu, China, 2Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China, 3MR Collaboration, Siemens Healthineers Ltd., Shanghai, China


This study evaluated right ventricular (RV) functional changes using cardiac magnetic resonance (CMR) tissue tracking and the association of these changes with fat distributions in obese adults with no clinical signs or comorbidities. The results showed that CMR tissue tracking can detect subclinical RV dysfunction with preserved RV ejection fraction in obese adults. Central obesity, represented by android fat, trunk fat, and the android/gynoid fat mass ratio, had a deleterious effect on RV subclinical dysfunction, whereas peripheral obesity (gynoid fat) might have had a protective effect. These findings could contribute to more precise obesity management in clinical practice.

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