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Abstract #4176

Venous Response in Brains with Ischemic Stroke Assessed with Susceptibility-Based MR Imaging

Shihui Zhou1,2, Zhiqiang Wei3, Yulong Qi4, Li Yi3, Siqi Cai1,2, Chunxiang Jiang1,2, and Lijuan Zhang*1
1Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 2University of Chinese Academy of Sciences, Beijing, China, 3Department of Neurology, Peking University Shenzhen Hospital, Shenzhen, China, 4Department of Radiology, Beijing University Shenzhen Hospital, Shenzhen, China


Venous response has been overlooked in the characterization of ischemic stroke (IS). In this study, vein density (VD) and oxygen extraction fraction (OEF) were assessed as indices of venous response for both the ipsi- and contra-lesional hemispheres in a cohort of patient with corona radiata IS using susceptibility MR imaging. Relative VD and OEF (ratios between the averaged ipsilesional and contralesional measurements) increased from early (1-7 days) to late subacute stages of IS (7-15 days). Patients with lesion in right corona radiata showed more extensive interhemispheric difference in OEF, suggesting an anatomy specific distribution of the venous response after IS.

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