Time estimation from stroke onset with diffusion-relaxation matrix-based T2 and ADC simultaneous mapping
Hajime Yokota1, Takayuki Sakai2, Masami Yoneyama3, and Takashi Uno1
1Department of Diagnostic Radiology and Radiation Oncology, Chiba University, Chiba, Japan, 2Department of Radiology, Eastern Chiba Medical Center, Togane, Japan, 3Philips Japan, Tokyo, Japan
Diffusion-relaxation matrix (DRM) sequence consists of dual-echo single-shot DW-EPI. DRM was able to detect acute cerebral infarction as well as conventional DWI, and can simultaneously acquire ADC and T2 values. T2 values in the infarcted area correlated significantly with time since stroke onset, whereas ADC did not. In addition, T2 values could predict whether the infarct was within 4.5, 6, or 16 hours, which are the thresholds for thrombolysis and endovascular treatment.
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