In some cases, treatment of severe liver diseases requires resective surgery. This brings serious complications if the remnant tissue fails to match the requirement of liver function. Therefore, a pre-operative risk assessment is vital. However, usually the assessment only investigates global liver function. For a more precise assessment, we investigate the possibility of using DCE-MRI in combination with pharmacokinetic modeling to quantify both global- and regional liver function. Also, we show a novel eight-compartment hepatic model, capable of performing an in-silico resection. This framework might in the future be used as a tool for a more precise pre-operative assessment.
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