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Abstract #4203

DKI and IVIM for Assessment of Rectal Cancer: Correlations between Imaging Parameters and Tumor Tissue Composition

Jie Yuan1, Mengxiao Liu2, Songhua Zhan1, Zhigang Gong1, and Qiang Shen1
1Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, 2MR scientific Marketing, Diagnostic Imaging, Siemens Healthineers Ltd, Shanghai, China


It is important to combine histopathological and non-invasive imaging measurements to assess tumor components and predict tumor invasiveness to define disease treatment and prognostic assessment. In this study, we assessed the relationships between DKI and IVIM parameter measurements and the corresponding tumor tissue composition, regardless of the status of the malignant tumor. To this end, we selected a range of tissue parameters informative for important biological properties of the tumor, such as Ki-67, the tumor: stroma ratio, CD34 etc.

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