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Abstract #4204

Application of native T1 mapping for distinguishing histopathologic subtypes, grades, and stages of rectal adenocarcinoma

Juan Li1, Marcel Dominik Nickel2, cheng jingliang1, and Zhu Jinxia 3
1Department of MRI, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, 3MR collaboration, Siemens Healthcare Ltd., Beijing, China

Synopsis

This study evaluated the clinical significance of using native T1 mapping for distinguishing histopathologic subtypes, grades, and stage of rectal adenocarcinoma by measuring parameters such as T1 relaxation time and apparent diffusion coefficient (ADC). The results showed that T1 and ADC values were significantly higher in rectal mucinous adenocarcinoma (MC) compared to non-mucinous rectal adenocarcinoma (AC). In the AC group, T1 values were significantly lower in the low-grade AC than in the high-grade AC. Our findings suggest that native T1 mapping can distinguish histopathologic subtypes of renal adenocarcinoma. Moreover, T1 values distinguish different grades of AC more accurately than ADC values.

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