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Abstract #4206

Comparative Study of histogram analysis of Intravoxel Incoherent Motion and Diffusion Kurtosis Imaging for the staging of liver fibrosis

Fengxian Fan1, Yanli Jiang1, Jing Zhang1, Jie Zou1, and Jialiang Ren2
1Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China, 2GE Healthcare, Shanghai, China


The purpose of this study is to compare the diagnostic accuracy of histogram analysis–derived parameters from intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) for staging of liver fibrosis (LF). The correlations between different histopathologic stages and histogram parameters were determined. The results showed that the histogram metrics of DKI maps demonstrate significant correlation with fibrosis stage, while there was no correlation between histogram metrics of IVIM and fibrosis stage. In conclusion, histogram analysis of DKI may serve as a valuable and robust tool for the staging of LF.

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