A total of 214 patients with pathologically confirmed Hepatocellular carcinoma (HCC) who underwent gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) before curative resection between July 2015 and November 2020 were retrospectively included in this study. The preoperative model integrating EOB-MRI findings and serum AFP and AST levels achieved accurate recurrence prediction in HCC, with similar performance to that of the postoperative clinical-radiologic-pathologic model. Moreover, the preoperative model yielded superior predictive performance to four widely used clinical staging systems for HCC recurrence prediction. This model offered a potential noninvasive and reliable approach for individualized recurrence risk estimation before hepatectomy.
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