Abstract #4214
Evaluation of amide proton transfer-weighted imaging and stretch index diffusion imaging for lung cancer staging and its correlation with Ki67
Pengyang Feng1, Nan Meng2, Zhun Huang1, Ting Fang2, Ziqiang Li3, Fangfang Fu4, Wei Wei4, Yan Bai4, Yang Yang5, Jianmin Yuan6, and Meiyun Wang*1
1Department of Radiology, Henan University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China, 2Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China, 3Xinxiang Medical University & Henan Provincial People's Hospital, Xinxiang, China, 4Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou, China, 5UIH Group, Central Research Institute, Beijing, China, 6UIH Group, Central Research Institute, Shanghai, China
Synopsis
Amide proton transfer-weighted imaging (APTWI) primarily reflects the protein content and acidity information of tissue structures. Stretch index diffusion imaging includes α, DDC values, these parameters reflect the heterogeneous characteristics of tumors. Ki67 is a good indicator to evaluate the proliferative activity of tumor cells. The results showed that APTWI and stretch index diffusion imaging had similar diagnostic performance in the diagnosis of lung cancer staging，and there was a certain correlation between the parameters and Ki67.
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