Abstract #4214

Evaluation of amide proton transfer-weighted imaging and stretch index diffusion imaging for lung cancer staging and its correlation with Ki67

Pengyang Feng¹, Nan Meng², Zhun Huang¹, Ting Fang², Ziqiang Li³, Fangfang Fu⁴, Wei Wei⁴, Yan Bai⁴, Yang Yang⁵, Jianmin Yuan⁶, and Meiyun Wang*¹

¹Department of Radiology, Henan University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China, ²Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China, ³Xinxiang Medical University & Henan Provincial People's Hospital, Xinxiang, China, ⁴Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou, China, ⁵UIH Group, Central Research Institute, Beijing, China, ⁶UIH Group, Central Research Institute, Shanghai, China

Synopsis

Amide proton transfer-weighted imaging (APTWI) primarily reflects the protein content and acidity information of tissue structures. Stretch index diffusion imaging includes α, DDC values, these parameters reflect the heterogeneous characteristics of tumors. Ki67 is a good indicator to evaluate the proliferative activity of tumor cells. The results showed that APTWI and stretch index diffusion imaging had similar diagnostic performance in the diagnosis of lung cancer staging，and there was a certain correlation between the parameters and Ki67.

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