Stage liver fibrosis and inflammatory activity using radiomic models based on easy access magnetic resonance images
Huanhuan Wei1, Fangfang Fu2, Yaping Wu2, Yan Bai2, Nan Meng1, Wei Wei2, Kewei Liu3, Xianchang Zhang4, and Meiyun Wang2
1Academy of Medical Sciences, the People’s Hospital of Zhengzhou University, Zhengzhou, China, 2Department of Medical Imaging, Henan Provincial People's Hospital & the People’s Hospital of Zhengzhou University, Zhengzhou, China, 3The First People's Hospital of Zhoukou, Zhoukou, China, 4MR Collaboration, Siemens Healthineers Ltd, Beijing, China
Invasive pathological puncture biopsy is the diagnostic standard for liver fibrosis (LF), but it has certain risks and low repeatability. A non-invasive and reliable method is essential for early detecting and staging of LF. To this end, this study explored the feasibility of using radiomics approach based on easy access T1-weighted and T2-weighted fat saturation magnetic resonance imaging data to stage the liver fibrosis and inflammatory activity. The receiver operating curves analysis demonstrated that the trained radiomic models could effectively stage the LF and inflammatory activity with a high efficacy.
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