Abstract #4225

Stage liver fibrosis and inflammatory activity using radiomic models based on easy access magnetic resonance images

Huanhuan Wei¹, Fangfang Fu², Yaping Wu², Yan Bai², Nan Meng¹, Wei Wei², Kewei Liu³, Xianchang Zhang⁴, and Meiyun Wang²

¹Academy of Medical Sciences, the People’s Hospital of Zhengzhou University, Zhengzhou, China, ²Department of Medical Imaging, Henan Provincial People's Hospital & the People’s Hospital of Zhengzhou University, Zhengzhou, China, ³The First People's Hospital of Zhoukou, Zhoukou, China, ⁴MR Collaboration, Siemens Healthineers Ltd, Beijing, China

Synopsis

Invasive pathological puncture biopsy is the diagnostic standard for liver fibrosis (LF), but it has certain risks and low repeatability. A non-invasive and reliable method is essential for early detecting and staging of LF. To this end, this study explored the feasibility of using radiomics approach based on easy access T1-weighted and T2-weighted fat saturation magnetic resonance imaging data to stage the liver fibrosis and inflammatory activity. The receiver operating curves analysis demonstrated that the trained radiomic models could effectively stage the LF and inflammatory activity with a high efficacy.

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