During the evolution of hepatocellular carcinoma(HCC) from high differentiation to low differentiation, the number of tumor cells increased and arranged more closely, the limited diffusion of water molecules was more obvious. Meanwhile, the iron and fat content in the lesions decreased gradually. The ADC、D values derived from IVIM-DWI and FF、R2* values derived from IDEAL-IQ can accurately reflect the diffusion limitation and the changes of fat and iron content in HCC, so as to accurately evaluate the pathological grade of HCC.
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