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Abstract #4227

The value of different diffusion models in evaluating liver regeneration after standard partial hepatectomy in rats

caixin Qiu1, shuangshuang xie1, yajie Sun2, yongquan Yu3, xuyang Wang2, jinxia Zhu4, Grimm Robert5, and wen Shen2
1Radiology Department, Tianjin First Center Hospital, TIANJIN, China, 2Tianjin First Center Hospital, TIANJIN, China, 3Weihai Central Hospital, SHAN DONG, China, 4MR Collaboration, Siemens Healthcare Ltd., BEIJING, China, 5MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany


Different diffusion weighted imaging (DWI) models were used to evaluate microscopic changes of residual liver in rats after standard partial hepatectomy (70%PH). Multiple b-value DWI at multiple timepoints after 70%PH were acquired, and the data was analyzed using three diffusion models: conventional monoexponential DWI, intravoxel incoherent motion (IVIM), and diffusion kurtosis imaging (DKI) models. Compared with the monoexponential model of DWI, IVIM and DKI models can describe the changes of blood supply in the process of liver regeneration and provide added value in evaluating the microstructure of liver regeneration after standard partial hepatectomy.

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