We evaluated relationships between age and shifted apparent diffusion coefficient, proton density fat fraction (PDFF), and pancreas size using 3-T MRI. PDFF increased with age, and anterior-posterior diameters decreased with age. Interestingly, elasticity of the pancreas decreased with age. Based on these results, decreases in the size of the pancreatic parenchyma with age appear attributable to not only fibrosis, but also fatty degeneration, resulting in decreased elasticity. Fat content should be evaluated at the same time as fibrosis of the pancreatic parenchyma.
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