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Abstract #4246

Radiomics based on biparametric MRI for the detection of significant residual prostate cancer after androgen deprivation therapy

Xiaohang Liu1, Zhangzhe Chen1, Weijie Gu1, Bingni Zhou1, Wei Liu1, Hualei Gan1, Yong Zhang2, and Liangping Zhou1
1Fudan University Shanghai Cancer Center, Shanghai, China, 2GE Healthcare, Shanghai, China


The purpose of this study was to use the radiomics method to differentiate prostate cancer and benign peripheral zone (PZ) tissues and investigate its ability to detect significant residual prostate cancer based on whole-mount pathology. The mean ADC of significant residual lesions was significantly lower than that of CR/MRD, which was significantly lower than that of benign tissues. The efficiency of the radiomics models was similar to that of ADC in distinguishing CR/MRD from benign tissue and distinguishing residual from benign tissue. The radiomics models showed superior efficiency in differentiating significant residual from CR/MRD as compared to ADC.

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