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Abstract #4245

Application of synthetic MRI to diagnose benign and malignant breast masses: APTw imaging combined with T1 Mapping and DWI imaging

Jie Ding1, Zhen Zhang1, Rui Wang 1, Xiuzheng Yue2, Rongrong Zhu1, and Ruoshui Ha1
1Medical Imaging Center, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China, 2Philips Healthcare, Beijing, China

Synopsis

Breast cancer has surpassed lung cancer to become the world's largest cancer for the first time, and the cancer mortality rate ranks second, showing a younger trend in recent years. APTw imaging, as a noninvasive molecular imaging technique, can measure the concentration of free proteins and polypeptides in tissues without the use of exogenous contrast agents, based on a chemical exchange between amide protons and water protons. The aim of study was to explore the diagnostic efficacy for benign and malignant breast tumor by using synthetic MRI.

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