Abstract #4244

Development and validation of a semi-automated framework for PI-RADS v2.1 assessment

Dharmesh Singh¹, Virendra Kumar², Chandan J Das³, Anup Singh^1,4, and Amit Mehndiratta^1,4

¹Centre for Biomedical Engineering (CBME), Indian Institute of Technology (IIT) Delhi, New Delhi, India, ²Department of NMR, All India Institute of Medical Sciences (AIIMS) Delhi, New Delhi, India, ³Department of Radiodiagnosis, All India Institute of Medical Sciences (AIIMS) Delhi, New Delhi, India, New Delhi, India, ⁴Department of Biomedical Engineering, All India Institute of Medical Sciences (AIIMS) Delhi, New Delhi, India, New Delhi, India

Synopsis

Prostate Imaging-Reporting and Data System version 2.1 (PI-RADS v2.1) was developed to standardize the interpretation of multiparametric MRI (mpMRI) for prostate cancer (PCa) detection. However, a significant inter-reader variability among radiologists has been found in the PI-RADS assessment. An automated or semi-automated PI-RADS assessment system could be beneficial in the screening process of PCa and could improve the consistency of scoring. The purpose of this study was to evaluate the diagnostic performance of an in-house developed semi-automatic framework for PI-RADS assessment using machine learning classifiers.

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