Abstract #4249

The value of IVIM and enhanced T2star weighted angiography for preoperatively predicting Ki-67 status in hepatocellular carcinoma

Qihao Xu¹, Ying Zhao¹, Wenjing Qi², Xue Ren¹, Tao Lin¹, Qingwei Song¹, and Ailian Liu^1,3

¹Department of Radiology, The First Affiliated Hospital, Dalian Medical University, Dalian, Liaoning, China, China, ²Department of Pathology, The First Affiliated Hospital, Dalian Medical University, Dalian, Liaoning, China, China, ³Dalian Engineering Research Center for Artificial Intelligence in Medical Imaging, Dalian, Liaoning, China

Synopsis

In hepatocellular carcinoma (HCC) patients, high Ki-67 was closely related with tumor size, vein invasion, histological grade and the metastasis. This worked aimed at investigating the value of intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance (MR) imaging and enhanced T2star weighted angiography(ESWAN) for predicting tumor Ki-67 status in HCC. The results showed that Standard ADC, DDC, R2*, T2* and combine had promising performances in predicting Ki-67 status. This research suggested that the IVIM and ESWAN held great potential in predicting the Ki-67 status of HCC, which is valuable for noninvasively, preoperatively and accurately predicting the prognostic factors during clinical practice.

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