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Abstract #4258

The spectrum of MRI-PDFF, MRS, and two different histopathologic methods (AI vs. pathologist) in the quantification of hepatic steatosis

Jeong Woo Kim1 and Chang Hee Lee2
1Radiology, Korea University Guro Hospital, Seoul, Korea, Republic of, 2Korea University Guro Hospital, Seoul, Korea, Republic of


The aim of our study was to 1) provide spectrum of values of multi-echo mDixon MRI-PDFF, FFMRS, and FFs measured by two different histopathologic methods (pathologist and automatic fat vacuole segmentation), and 2) to evaluate the correlation among them. The values of MRI-PDFF and FFMRS were significantly higher than FFAI and significantly lower than FFpathologist. Except for one case (97.9%,46/47), FFMRS always showed higher value than MRI-PDFF and the average difference was 2.06 %. MRS and MRI-PDFF showed strong correlation with each other and with each histopathologic method. MRI-PDFF or MRS could be used as an alternative non-invasive reference standard.

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