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Abstract #4279

Apparent Diffusion Coefficient of Different Diffusion Times for Differentiation of Benign and Malignant Breast Tumors

Jie Ding1, Yishi Wang2, Zhen Zhang1, Xiuzheng Yue2, Rongrong Zhu1, and Ruoshui Ha1
1Medical Imaging Center, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China, 2Philips Healthcare, Beijing, China


Some novel biomarkers has emerged from the fact that apparent diffusion coefficient (ADC) depends strongly on the diffusion time, such as the rate of ADC change using two diffusion times for the differentiation of breast tumor types and a cell size modeling. In this study, we propose to use Multiband (MB) SENSE to accelerate the data acquisition of OGSE and PGSE sequences and compare the diagnostic value of ADC at different diffusion times for breast tumor. Our data showed superior diagnostic performance between benign and malignant breast lesions using ADC at a short diffusion time.

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