We evaluated amide- and amine-CEST signal of brain tumors on a 3 Tesla MR scanner with conventional Z-spectrum and MTRasym analysis. Subjects were eight patients with brain tumor. There were significant differences between mean MTRasym values at 0.2 and 0.35 ppm offset frequencies (P < 0.05). Our findings was able to evaluate brain tumor characteristics with multi-pool analysis on the positive side of offset frequency on a 3 Tesla MRI scanner.
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